For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | IL-5 is an important cytokine primarily produced by Th2 cells, mast cells, and eosinophils. IL-5 plays a critical role in the development, proliferation, and activation of eosinophils and is essential for their differentiation and survival. Additionally, IL-5 regulates B cell growth and differentiation, promoting the production of IgM and IgA. In immune responses, IL-5 activates the JAK-STAT signaling pathway by binding to its receptor IL-5Rα/β, modulating various cellular functions. IL-5 is significantly involved in allergic diseases (such as asthma) and parasitic infections, with elevated levels associated with eosinophilia. |
Alternate Names | - |
Uniprot ID | P08928 |
Clone No | TRFK5 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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