For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | IL-2 is a key immunoregulatory cytokine primarily produced by activated T cells. It plays an essential role in the proliferation, differentiation, and survival of T cells and also promotes the activation of natural killer (NK) cells. IL-2 exerts its effects by binding to its receptor complex, which includes IL-2Rα, IL-2Rβ, and IL-2Rγ subunits, with the high-affinity receptor being particularly important in modulating immune responses. IL-2 not only enhances the function of immune cells but also regulates the homeostasis of regulatory T cells (Treg) to maintain immune tolerance. Additionally, IL-2 is critically involved in antitumor immunity and autoimmune diseases, making it an important target for immunotherapy. Recombinant mouse IL-2 is widely used in research to simulate immune responses under physiological and pathological conditions. |
Alternate Names | TCGF |
Uniprot ID | P04351 |
Clone No | JES6-1A12 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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