For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD62E is a type I transmembrane glycoprotein and a member of the selectin family, primarily expressed on activated endothelial cells. It is upregulated by proinflammatory cytokines such as IL-1, TNF-α, and LPS, and plays a crucial role in inflammatory responses. CD62E mediates the initial adhesion and rolling of leukocytes on endothelial cells, facilitating their recruitment to sites of inflammation. Additionally, CD62E can be secreted and detected in a soluble form (sE-selectin) in serum. In mouse models, the expression of CD62E is closely associated with various inflammation-related diseases, making it an important target for studying inflammatory mechanisms and immune responses. |
Alternate Names | E-Selectin |
Uniprot ID | P16581 |
Clone No | 9A9 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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