For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD83 is a member of the immunoglobulin superfamily, with a molecular weight of approximately 43 kDa and is a transmembrane protein. It is primarily expressed on the surface of mature dendritic cells (DCs) and serves as a key marker for mature DCs. Additionally, CD83 is expressed on natural killer cells, activated macrophages, neutrophils, and activated T and B cells. CD83 plays an important regulatory role in immune responses, promoting the activation and proliferation of T lymphocytes while also inhibiting their background activity. In B cells, CD83 is crucial for activation, maturation, homeostasis, and antibody responses. Moreover, CD83 is involved in the differentiation and stability of regulatory T cells (Tregs). During infections, the expression level of CD83 affects antibody production and the function of immune cells. |
Alternate Names | HB15 |
Uniprot ID | Q01151 |
Clone No | Michel-17 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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