For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD48 is an important member of the signaling lymphocyte activation molecule family (SLAMF) and a glycosylphosphatidylinositol (GPI)-anchored immunostimulatory and adhesion molecule, widely expressed on the surface of immune cells in mice, such as B cells, T cells, NK cells, mast cells, and eosinophils. It participates in cell adhesion and signaling by interacting with ligands like CD2 and CD244 (2B4), and is involved in the regulation of immune responses, inflammatory reactions, and cell proliferation and survival. In tumor immunology, aberrant expression of CD48 is closely related to tumor immune evasion, and its role in the tumor microenvironment has attracted attention. Additionally, CD48 is also important in the sorting of hematopoietic stem cells, for example, it is commonly used to distinguish subpopulations of hematopoietic stem cells in mouse hematopoietic stem cell flow cytometry analysis. |
Alternate Names | BCM1 |
Uniprot ID | P18181 |
Clone No | HM48-1 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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