For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD370 is a member of the C-type lectin receptor family and is selectively expressed on subsets of myeloid cells, such as plasmacytoid dendritic cells and CD8⁺ myeloid dendritic cells. It is a type II transmembrane protein with a C-type lectin domain that recognizes F-actin, an antigen exposed in necrotic cells. CD370 recruits Syk kinase upon ligation, mediating cross-presentation of necrotic cell-associated antigens and promoting immune responses. Additionally, CD370 is significant in the fields of immunology, cancer biology, and innate immunity. |
Alternate Names | CLEC9A |
Uniprot ID | Q99IW5 |
Clone No | 7H11 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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