For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD314 is a type II transmembrane glycoprotein expressed on natural killer (NK) cells, cytotoxic T lymphocytes (CTLs), and some dendritic cell subsets. NKG2D recognizes stress-induced ligands (such as MICA, MICB, and ULBP family members) and plays a crucial role in immune surveillance. It activates NK cells in innate immune responses and serves as a costimulatory receptor for CD8⁺ T cells, enhancing adaptive immune responses. Additionally, NKG2D mediates target cell lysis through perforin and is involved in NK cell-mediated rejection of bone marrow transplants. Given its key role in immune surveillance, CD314 has emerged as a potential target for cancer immunotherapy and antiviral treatments. |
Alternate Names | NKG2D |
Uniprot ID | P26718 |
Clone No | CX5 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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