For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD262 is a member of the tumor necrosis factor receptor superfamily and a type I transmembrane protein. It is widely expressed in various cell types, including immune cells and tumor cells. CD262 is one of the receptors for TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), a cytokine that induces apoptosis. CD262 transmits apoptotic signals through its intracellular death domain (DD) and plays a role in regulating apoptosis. In the immune system, CD262 activation can induce apoptosis in tumor cells, making it a potential target for cancer immunotherapy. Additionally, CD262 is involved in regulating the survival and function of immune cells, influencing inflammatory responses and autoimmune diseases. |
Alternate Names | TNFRSF10B/DR5 |
Uniprot ID | Q9Z0Y6 |
Clone No | MD5-1 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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