For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD206 is a C-type lectin receptor belonging to the pattern recognition receptor family. It is primarily expressed on macrophages, dendritic cells, endothelial cells, and microglia. CD206 recognizes and binds to glycosylated components of pathogens, facilitating the clearance of pathogens and apoptotic cell debris through endocytosis. It plays a crucial role in both innate and adaptive immunity. Additionally, CD206 is a marker for M2-type macrophages, which are characterized by their anti-inflammatory, tissue repair, and immune regulatory functions. In the tumor microenvironment, CD206-high macrophage subsets (e.g., CD206hiMHCIIlo) can promote fibrosis and tumor progression by secreting cytokines such as TGF-β1. Therefore, CD206 is not only an important marker for studying macrophage polarization and immune regulation but also a potential therapeutic target for diseases. |
Alternate Names | MRC1 |
Uniprot ID | Q61830 |
Clone No | - |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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