For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD205 is a C-type lectin receptor primarily expressed on dendritic cells (DCs), Langerhans cells, bone marrow-derived DCs, and thymic epithelial cells. As an endocytic receptor, CD205 captures antigens and transports them to specialized processing compartments, playing a crucial role in immune surveillance and the initiation of immune responses. Additionally, CD205 is involved in regulating B lymphocyte proliferation by inhibiting excessive responses. In tumor immunology, targeting CD205 can enhance anti-tumor immune responses by activating dendritic cells. Therefore, CD205 is not only an important target for studying immune regulation but also shows potential for application in cancer immunotherapy. |
Alternate Names | DEC-205/ LY75 |
Uniprot ID | Q60767 |
Clone No | NLDC-145 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
會員登錄
