For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD18 is the β2 subunit of the integrin family and a 95 kD transmembrane protein encoded by the ITGB2 gene. It is primarily expressed on the surface of leukocytes and can form complexes with different integrin α subunits, such as CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1). These complexes play crucial roles in immune responses, including leukocyte adhesion, migration, and cell-to-cell interactions. CD18 is essential in leukocyte adhesion deficiency, where its absence prevents leukocytes from migrating from the bloodstream to tissues. Additionally, CD18 is involved in inflammation and immune regulation, making it an indispensable molecule in the immune system. |
Alternate Names | ITGB2/LFA-1β |
Uniprot ID | P11835 |
Clone No | M18/2 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
會員登錄
