For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD178 is a type II transmembrane protein belonging to the tumor necrosis factor family. It is primarily expressed in activated T cells and natural killer (NK) cells. CD178 induces apoptosis by binding to its receptor Fas, playing a crucial role in immune system regulation, including activation-induced cell death (AICD) and cytotoxic T cell-mediated cell death. Additionally, defects in CD178 are associated with autoimmune diseases such as systemic lupus erythematosus. In mice, deficiency in CD178 can lead to lymphoproliferation and autoimmune disorders. |
Alternate Names | CD95L/TNFSF6 |
Uniprot ID | P41047 |
Clone No | MFL3 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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