For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Background | CD16.2 is a member of the immunoglobulin superfamily and a low-affinity receptor for IgG and IgE, predominantly expressed on immune cells such as monocytes, macrophages, dendritic cells, and neutrophils. In mice, CD16.2 mediates antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis by binding to IgG2a and IgG2b. Additionally, CD16.2 is involved in regulating IgE-induced inflammatory responses, promoting lung inflammation. Studies have shown that CD16.2 is crucial for immune system balance, with its deficiency leading to impaired IgG-dependent effector functions. |
Alternate Names | FcγRIV/CD16-2 |
Uniprot ID | P08508 |
Clone No | 9E9 |
Host | Rat |
Reactivity | Mouse |
Isotype control | / |
Application | Flow cytometry |
Conjugation | FITC, PE, APC, PE-Cy7, APC-Cy7, PerCP |
Conjugation Information | 488/785，488/578，650/660，488/785，650/785，488/677 |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | 2~8℃, Samples were stored at -20 °C for a long time to avoid repeated freezing and thawing. |
Expiration date | 24M |
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